New PDF release: Bacillus anthracis - A Medical Dictionary, Bibliography, and

By Icon Health Publications

ISBN-10: 0497001187

ISBN-13: 9780497001186

ISBN-10: 141754287X

ISBN-13: 9781417542871

This can be a 3-in-1 reference publication. It supplies an entire scientific dictionary overlaying hundreds of thousands of phrases and expressions when it comes to Bacillus anthracis. It additionally provides wide lists of bibliographic citations. eventually, it offers info to clients on find out how to replace their wisdom utilizing a variety of net assets. The booklet is designed for physicians, clinical scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to get to grips with examine devoted to Bacillus anthracis. in case your time is efficacious, this publication is for you. First, you won't waste time looking the net whereas lacking loads of suitable details. moment, the ebook additionally saves you time indexing and defining entries. eventually, you won't waste money and time printing thousands of web content.

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Extra resources for Bacillus anthracis - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

Sample text

The X-ray structure of diphtheria, anthrax toxin, and botulinum toxin A is known. BLAST analysis of these toxins has suggested the presence of 12 amino acid "entry motif" in each toxin. The present application proposes the continuing study of diphtheria toxin C-domain, alanine scanning mutagenesis of the putative "entry motif", and the development of an in vitro translocation assay for anthrax lethal factor. In the case of diphtheria toxin, anthrax toxins, and botulinum toxins a great deal is known of their respective structure function domains and their mode of action; however, a detailed understanding of the molecular mechanism(s) required for translocation of their respective catalytic domains from the lumen of acidified early endosomes to the cytosol have remained elusive.

3. to array biosensors that respond to different effectors upon a chip for the rapid detection of pathogen markers. The biosensors generated in this study will streamline disease diagnosis by supplanting time-consuming and expensive immunoassays. These experiments will test the feasibility of our evolutionary hypothesis and demonstrate the utility of novel protein engineering techniques. Generate_Screen Studies • 29 Project Title: ESCAPE OF BACILLUS ANTHRACIS FROM THE PHAGOSOME Principal Investigator & Institution: Goldfine, Howard; Professor; Microbiology; University of Pennsylvania 3451 Walnut Street Philadelphia, Pa 19104 Timing: Fiscal Year 2003; Project Start 30-SEP-2003; Project End 31-AUG-2005 Summary: (provided by applicant): In the pulmonary form of anthrax caused by the pathogen Bacillus anthracis (Ba), spores in the lung are ingested by macrophages.

3) Generate, from selected animals, an initial series of human monoclonal antibodies specific for PA, and possibly LF. These will be characterized for neutralizing activity, and using BIACORE, affinity and epitope grouping. The main goal of the phase II proposal will be the configuration of at least one combination of human monoclonals which could be evaluated in vivo for the ability to protect and/or rescue from B. anthracis challenge. The phase II SBIR program may require the generation of a larger panel of antibodies, based on the success of phase I.

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Bacillus anthracis - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications

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